How is lh produced

Administration of FSH to humans and animals induces "superovulation", or development of more than the usual number of mature follicles and hence, an increased number of mature gametes. FSH is also critical for sperm production. It supports the function of Sertoli cells, which in turn support many aspects of sperm cell maturation. GnRH is a ten amino acid peptide that is synthesized and secreted from hypothalamic neurons and binds to receptors on gonadotrophs.

As depicted in the figure to the right, GnRH stimultes secretion of LH, which in turn stimulates gonadal secretion of the sex steroids testosterone, estrogen and progesterone. In a classical negative feedback loop , sex steroids inhibit secretion of GnRH and also appear to have direct negative effects on gonadotrophs.

In females, pulse frequency is clearly related to stage of the cycle. Numerous hormones influence GnRH secretion, and positive and negative control over GnRH and gonadotropin secretion is actually considerably more complex than depicted in the figure. For example, the gonads secrete at least two additional hormones - inhibin and activin - which selectively inhibit and activate FSH secretion from the pituitary.

This condition is typically manifest in males as failure in production of normal numbers of sperm. Human body. Home Hormones Luteinising hormone. Luteinising hormone Luteinising hormone is produced by the pituitary gland and is one of the main hormones that control the reproductive system.

Alternative names for luteinising hormone Interstitial cell stimulating hormone; luteinizing hormone; lutropin; LH What is luteinising hormone? How is luteinising hormone controlled?

What happens if I have too much luteinising hormone? What happens if I have too little luteinising hormone? Last reviewed: Feb Prev. Melanocyte-stimulating hormone. Related Glands. Related Endocrine Conditions. Klinefelter's syndrome Polycystic ovary syndrome Turner syndrome Amenorrhoea Premature ovarian failure Female infertility View all Endocrine conditions.

These include some of the symptoms listed above, as well as: Fatigue Weakness Weight loss Decreased appetite Your child may need an LH test if he or she is does not seem to be starting puberty at the right age either too early or too late. What happens during an LH levels test?

Will I need to do anything to prepare for the test? Are there any risks to the test? What do the results mean? The meaning of your results will depend on whether you are a woman, man, or child. If you are woman, high LH levels may mean you: Are not ovulating.

If you are of childbearing age, this may mean you have a problem in your ovaries. If you are older, it may mean you have started menopause or are in perimenopause. Have polycystic ovary syndrome PCOS. PCOS is a common hormone disorder affecting childbearing women. It is one of the leading causes of female infertility. Have Turner syndrome , a genetic disorder affects sexual development in females.

It often causes infertility. If you are woman, low LH levels may mean: Your pituitary gland is not working correctly. You have an eating disorder.

You have malnutrition. If you are a man, high LH levels may mean: Your testicles have been damaged due chemotherapy , radiation, infection, or alcohol abuse. You have Klinefelter's syndrome , a genetic disorder that affects sexual development in males. It often causes infertility If you are a man, low LH levels may mean you have a disorder of the pituitary gland or the hypothalamus, a part of the brain that controls the pituitary gland and other important body functions.

If this is happening before age 9 in a girl or before age 10 in a boy precocious puberty , it may be a sign of: A disorder of the central nervous systems A brain injury Low LH and follicle-stimulating hormone levels in children may mean be a sign of delayed puberty. Delayed puberty may be caused by: A disorder of the ovaries or testicles Turner syndrome in girls Klinefelter's syndrome in boys An infection A hormone deficiency An eating disorder If you have questions about your results or child's results, talk to your health care provider.

Is there anything else I need to know about an LH test? Silver Spring MD : U. A tube attached to the needle will collect a small sample of your blood. The process is short and mostly painless. Your doctor may request that you have samples of blood drawn each day for several days.

Because the amount of LH in the blood varies with your menstrual cycle, a few samples may be necessary to get an accurate measurement of your LH levels.

The needle site may bruise afterwards, but if you put pressure on it with a bandage, you can reduce this possibility. Phlebitis , while rare, may occur when blood is drawn. This is when the vein becomes inflamed after blood is taken. If it occurs, your healthcare provider will likely have you apply a warm compress to the vein throughout the day.

If you have any kind of bleeding disorder, make sure to tell your doctor to avoid complications from having blood drawn. Your doctor should give you exact directions to prepare for your blood test. You may be told to stop taking certain medications that can affect the results, so be sure to inform your doctor of all medications and supplements you take. Your doctor will also want to know the date of your last period.

As with many blood draws, you may be asked to avoid eating or drinking for up to eight hours leading up to the test. These substances can interfere with the results of your test. Your doctor can tell you when results of your test will be available and will discuss the meaning of your levels with you. While each result can vary based on your unique condition, some general interpretations of LH results can include the following.

This is known as primary ovarian failure. Some causes of primary ovarian failure can include:. This means another part of your body causes ovarian failure. In many cases, this is the result of problems with the areas of your brain that make hormones, such as the pituitary gland. The causes of this condition can include:.